Turning pixels into acrylic is hard.
It's a great idea, and I totally get what you mean when you talk about the connection you have with the data and the memories it brings up as you make it. I like to think that some echoes of that live in the piece even when other people view it. When they see your brushstrokes, for instance, or when they read the hand-lettered names.
I once explored doing a stacked area graph using watercolours, because they go on translucent, allowing you to see the colours beneath. You've inspired me to try again.